Low Dose Spiral CT Features of Female Climacteric AIDS Complicated with Pulmonary Tuberculosis and the Association with CD4+T lymphocytes
Journal of Clinical Pulmonary Medicine 2017-1
Abstract：Objective To explore the low dose spiral CT features in female climacteric AIDS complicated with pulmonary tuberculosis and the association with CD4+T lymphocytes. Methods The study selected 55 cases with female climacteric AIDS complicated with pulmonary tuberculosis as the study group, and 42 female patients with climacteric pulmonary tuberculosis only as control group. The Results of CT scan and measurements of CD4+T lymphocytes were compared. Results （1） The CT scan features in the study group showed more patch consolidation （76. 8% vs 52. 3%, P<0. 05）, and less calcification （0 vs 51. 7%, P<0. 05）. There were statistic differences in the incidence of patch consolidation, multiple cavities, solitary cavernous, multiple nodules, pleural effusion, and lymph node enlargement between the two groups （P<0. 05）. （2） The relative number of CD4+T lymphocytes in the study group was less than that of the control group （P<0. 05）. In the study group, CD4+T lymphocyte counts were positively correlated with type Ⅰ pulmonary tuberculosis, and negatively correlated with type Ⅲ pulmonary tuberculosis （P<0. 05）, and had no correlation with type Ⅱ and Ⅳ pulmonary tuberculosis （P>0. 05）. The probability of involvement was negatively correlated with CD4+T lymphocyte counts classifications in the middle lobe of right lung and the inferior lobi of bilateral lungs （P<0. 05）, and negatively correlated with patch consolidation, multiple cavities, , multiple nodules, and lymph node enlargement （P<0. 05）. The probability of involvement was positively correlated with CD4+T lymphocyte counts classifications in solitary cavernous （P<0. 05）. There was no correlation between CD4+T lymphocyte count classifications and pleural effusion （P>0. 05）. Conclusion The low dose spiral CT features in female climacteric AIDS complicated with pulmonary tuberculosis are mostly atypical pattern, and they are closely related with a significant decrease in CD4+T lymphocyte count.
Keywords：CT, menopause, AIDS, tuberculosis, CD4+T lymphocyte count